A comprehensive safety and tolerability study evaluated approximately 900 participants across six trials with the following protocols: Subcutaneous/Intravenous Protocols: Single doses ranging from 25 to 400 mcg/kg body weight were tested
Megaloblastic anaemia of infancy and vitamin B 12
Patients should seek emergency medical help (call 999) if they experience: Difficulty breathing, wheezing, or throat tightness Swelling of the face, lips, tongue, or throat (angioedema) Widespread urticarial rash (hives) developing rapidly Dizziness, fainting, or rapid heartbeat suggesting anaphylaxis These symptoms typically occur within minutes to hours of administration, most commonly with injectable preparations
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They are typically administered intramuscularly (into the muscle)
Neither is universally superior